ZOE | Science & Nutrition
Change the way you eat, feel and live with ZOE.
Science is our superpower.
Now it’s yours.
We set out to test a bold question:
Can you transform your health in just 6 short weeks, using science-led nutrition?
We invited Sarah, Rob, and Lucy to take part in the experiment, each with very different lives and all dealing with low energy, poor sleep, and feeling not quite themselves.
There was no calorie counting or restrictive diets. Just changing how they eat to support their gut health, guided by ZOE’s world-leading scientists @tim.spector, @drsarahberry, and @dr.fede.amati.
We measured their health at the start and at the end of the 6 weeks, and documented everything in between.
In this experiment, there were no retakes and no controlled lab settings.
Just real life, with work, family, stress, holidays, and everything that makes changing your habits and improving your diet challenging.
Staying true to the science, we committed to sharing the results, no matter what happened.
So, did it work?
Watch The Gut Health Challenge on YouTube now, the link’s in our bio. 🎬
We can’t wait to hear what you think.

Today, we launch the next generation of ZOE in the UK.
After 8 years of running the world’s largest nutrition science study and listening to our members, we’re launching a brand-new ZOE App and Gut Health Test.
For the first time, you don’t need a test to join ZOE.
And if you do choose to test, you’ll unlock new insights from our Gut Microbiome Test.
From sequencing over 300,000 microbiomes, we’ve identified clusters of gut microbes linked to heart health, inflammation, blood sugar, and fat distribution. This makes it easier than ever to understand your gut health and take action to improve it.
Our App has also been rebuilt from the ground up. With mindful eating at its heart, we’ve created AI-powered tools powered by our microbiome database and the world’s largest nutrition study.
At ZOE, we take complex science and make it useful in your everyday life.
This is the next step in our mission to improve the health of millions, and we can’t wait for you to try it.
Comment ZIGGIE now and join us in the gut health revolution.💛

Today, we launch the next generation of ZOE in the UK.
After 8 years of running the world’s largest nutrition science study and listening to our members, we’re launching a brand-new ZOE App and Gut Health Test.
For the first time, you don’t need a test to join ZOE.
And if you do choose to test, you’ll unlock new insights from our Gut Microbiome Test.
From sequencing over 300,000 microbiomes, we’ve identified clusters of gut microbes linked to heart health, inflammation, blood sugar, and fat distribution. This makes it easier than ever to understand your gut health and take action to improve it.
Our App has also been rebuilt from the ground up. With mindful eating at its heart, we’ve created AI-powered tools powered by our microbiome database and the world’s largest nutrition study.
At ZOE, we take complex science and make it useful in your everyday life.
This is the next step in our mission to improve the health of millions, and we can’t wait for you to try it.
Comment ZIGGIE now and join us in the gut health revolution.💛

Today, we launch the next generation of ZOE in the UK.
After 8 years of running the world’s largest nutrition science study and listening to our members, we’re launching a brand-new ZOE App and Gut Health Test.
For the first time, you don’t need a test to join ZOE.
And if you do choose to test, you’ll unlock new insights from our Gut Microbiome Test.
From sequencing over 300,000 microbiomes, we’ve identified clusters of gut microbes linked to heart health, inflammation, blood sugar, and fat distribution. This makes it easier than ever to understand your gut health and take action to improve it.
Our App has also been rebuilt from the ground up. With mindful eating at its heart, we’ve created AI-powered tools powered by our microbiome database and the world’s largest nutrition study.
At ZOE, we take complex science and make it useful in your everyday life.
This is the next step in our mission to improve the health of millions, and we can’t wait for you to try it.
Comment ZIGGIE now and join us in the gut health revolution.💛

Today, we launch the next generation of ZOE in the UK.
After 8 years of running the world’s largest nutrition science study and listening to our members, we’re launching a brand-new ZOE App and Gut Health Test.
For the first time, you don’t need a test to join ZOE.
And if you do choose to test, you’ll unlock new insights from our Gut Microbiome Test.
From sequencing over 300,000 microbiomes, we’ve identified clusters of gut microbes linked to heart health, inflammation, blood sugar, and fat distribution. This makes it easier than ever to understand your gut health and take action to improve it.
Our App has also been rebuilt from the ground up. With mindful eating at its heart, we’ve created AI-powered tools powered by our microbiome database and the world’s largest nutrition study.
At ZOE, we take complex science and make it useful in your everyday life.
This is the next step in our mission to improve the health of millions, and we can’t wait for you to try it.
Comment ZIGGIE now and join us in the gut health revolution.💛

Today, we launch the next generation of ZOE in the UK.
After 8 years of running the world’s largest nutrition science study and listening to our members, we’re launching a brand-new ZOE App and Gut Health Test.
For the first time, you don’t need a test to join ZOE.
And if you do choose to test, you’ll unlock new insights from our Gut Microbiome Test.
From sequencing over 300,000 microbiomes, we’ve identified clusters of gut microbes linked to heart health, inflammation, blood sugar, and fat distribution. This makes it easier than ever to understand your gut health and take action to improve it.
Our App has also been rebuilt from the ground up. With mindful eating at its heart, we’ve created AI-powered tools powered by our microbiome database and the world’s largest nutrition study.
At ZOE, we take complex science and make it useful in your everyday life.
This is the next step in our mission to improve the health of millions, and we can’t wait for you to try it.
Comment ZIGGIE now and join us in the gut health revolution.💛

Today, we launch the next generation of ZOE in the UK.
After 8 years of running the world’s largest nutrition science study and listening to our members, we’re launching a brand-new ZOE App and Gut Health Test.
For the first time, you don’t need a test to join ZOE.
And if you do choose to test, you’ll unlock new insights from our Gut Microbiome Test.
From sequencing over 300,000 microbiomes, we’ve identified clusters of gut microbes linked to heart health, inflammation, blood sugar, and fat distribution. This makes it easier than ever to understand your gut health and take action to improve it.
Our App has also been rebuilt from the ground up. With mindful eating at its heart, we’ve created AI-powered tools powered by our microbiome database and the world’s largest nutrition study.
At ZOE, we take complex science and make it useful in your everyday life.
This is the next step in our mission to improve the health of millions, and we can’t wait for you to try it.
Comment ZIGGIE now and join us in the gut health revolution.💛

Today, we launch the next generation of ZOE in the UK.
After 8 years of running the world’s largest nutrition science study and listening to our members, we’re launching a brand-new ZOE App and Gut Health Test.
For the first time, you don’t need a test to join ZOE.
And if you do choose to test, you’ll unlock new insights from our Gut Microbiome Test.
From sequencing over 300,000 microbiomes, we’ve identified clusters of gut microbes linked to heart health, inflammation, blood sugar, and fat distribution. This makes it easier than ever to understand your gut health and take action to improve it.
Our App has also been rebuilt from the ground up. With mindful eating at its heart, we’ve created AI-powered tools powered by our microbiome database and the world’s largest nutrition study.
At ZOE, we take complex science and make it useful in your everyday life.
This is the next step in our mission to improve the health of millions, and we can’t wait for you to try it.
Comment ZIGGIE now and join us in the gut health revolution.💛

Today, we launch the next generation of ZOE in the UK.
After 8 years of running the world’s largest nutrition science study and listening to our members, we’re launching a brand-new ZOE App and Gut Health Test.
For the first time, you don’t need a test to join ZOE.
And if you do choose to test, you’ll unlock new insights from our Gut Microbiome Test.
From sequencing over 300,000 microbiomes, we’ve identified clusters of gut microbes linked to heart health, inflammation, blood sugar, and fat distribution. This makes it easier than ever to understand your gut health and take action to improve it.
Our App has also been rebuilt from the ground up. With mindful eating at its heart, we’ve created AI-powered tools powered by our microbiome database and the world’s largest nutrition study.
At ZOE, we take complex science and make it useful in your everyday life.
This is the next step in our mission to improve the health of millions, and we can’t wait for you to try it.
Comment ZIGGIE now and join us in the gut health revolution.💛
Did you know most of the corn grown across America can’t actually be eaten by humans?🌽
As @michael.pollan explains, you’d break your teeth trying. Instead, it’s processed into additives and ingredients that now make up a huge proportion of the modern diet.
At the same time, rates of chronic disease have risen alongside the growth of ultra-processed food. So how did our food system drift so far away from real food, and what should we be eating instead?
@michael.pollan is one of the most influential science writers of our time and a six-time bestselling author whose work has transformed how millions think about food and health.
@tim.spector is one of the world’s top 100 most-cited scientists and the scientific co-founder of ZOE.
Together, they explore:
- How modern agriculture reshaped the food on our plates
- Why ultra-processed foods are so difficult to stop eating
- Whether cravings are really about willpower
- And why eating more diverse plants may support better long-term health
Listen now via the link in bio or search “ZOE Science & Nutrition podcast”, and let us know what you think about the conversation.
Take it from two medical doctors and gut health experts: protein and fibre are not competing with each other biologically.
They do entirely different jobs.
Protein is primarily absorbed in the small intestine, where it’s broken down into amino acids used to build muscle, enzymes, hormones and immune cells. Fibre largely bypasses that process altogether.
Your body can’t digest most fibre, which is exactly why it’s so important. Instead, it travels down to the colon where trillions of gut microbes ferment it into compounds that help maintain your gut lining, regulate inflammation, influence appetite, and even communicate with your brain.
If you eat large amounts of protein without enough fibre, some of that excess protein reaches the colon instead. Your microbes then ferment the protein rather than fibre, producing compounds like ammonia and hydrogen sulphide, which may negatively affect the gut environment over time.
This is one reason why the healthiest long-term dietary patterns consistently include both adequate protein and plenty of diverse plant fibre. Protein for your human cells, and fibre for the trillions of microbial cells that live alongside them.
If you want me and @theguthealthmd to tackle any other nutrition misinformation, let us know in the comments.
There’s something disturbing about a slice of “cheese” that looks almost identical after 5 years in a cupboard.
Inspired by videos of fast food burgers and buns refusing to decompose, I decided to run my own little experiment. Much to my wife’s despair, this Kraft Singles slice has been sitting in our kitchen for half a decade.
Looking at it today raises an important question: if microbes, moulds and bacteria don’t seem interested in eating it… should we be?
Real cheese is a fascinating living food. Traditional cheeses are made through fermentation, where microbes transform milk over time into something nutritionally and chemically very different. In many aged cheeses, bacteria and fungi continue breaking down proteins and fats for months or even years, creating flavour, texture and thousands of bioactive compounds.
That’s what food normally does. It changes, it degrades, life interacts with it.
Ultra-processed cheese slices are something else entirely. They’re engineered to be hyper-stable: emulsifiers, refined oils, starches, flavourings and preservatives all designed to create a uniform product with a very long shelf life. And while technically edible, they’re very far removed from what humans have traditionally called cheese.
Your gut microbes evolved alongside real food. Fermented foods, fibres, complex plant compounds, slowly transformed ingredients.
Not fluorescent orange squares that survive half a decade untouched in a cupboard.
Comment COWBOY for the recipe. 🫘
Packing in 10 plants towards your 30 plants per week gut health goal, this salad-dip hybrid went viral for a reason.
It takes minutes to make and is the perfect pairing to ensure you still get plenty of fiber, polyphenols and plant diversity.
Make sure you save this video for next time someone asks you to bring a dish to a get-together this summer, and follow for more recipes to support your health goals.
What does the science say about saunas?
There’s some interesting research, particularly around heart health.
Large observational studies from Finland have found that people who use saunas more frequently tend to have lower risks of cardiovascular disease, stroke, and even death from all causes.
In one long-term study spanning 20 years, those having 4 to 7 saunas per week had a significantly lower risk of developing high blood pressure compared to those going once a week (PMID: 28633297). Other studies have linked frequent sauna use with reduced risk of stroke and heart disease.
There are also signals around brain health, with some research suggesting lower rates of dementia among regular sauna users, and even potential benefits for lung health.
But most of this evidence is observational. That means it can show associations, not cause and effect.
It may be that saunas are beneficial. But it may also be that people who use saunas regularly have other habits that support their health, like exercising more, having more leisure time, or lower stress levels.
Much of the research also comes from specific populations (mainly Scandinavian males), so we need to be cautious about generalising these findings more broadly.
So if you enjoy relaxing in a sauna, they may well offer some health benefits. But they’re not a substitute for the fundamentals of good nutrition, regular movement, and sleep.
I’d be interested to hear, are saunas part of your health routine?
Did you know there are trillions of viruses inside your gut right now?🦠
And if that isn’t surprising enough, some of them are playing an important role in keeping you healthy.
Professor Martha Clokie is a professor of microbiology at Leicester University and leading expert on bacteriophages — viruses that infect and destroy bacteria.
For the last 20 years, Martha has pioneered research to understand what these viruses, and whether she can develop bacteriophage therapy as a revolutionary approach to treat bacterial infections without antibiotics.
Together with @tim.spector, we explore a side of viruses that most of us have never heard about. We uncover:
- Why most viruses are completely harmless to humans
- How viruses in our gut help control the bacterial ecosystem we call the microbiome.
- Why some scientists believe phages could help solve the antibiotic resistance crisis
- How phage therapy has already been used to save patients with untreatable infections
- And what this hidden world of viruses may mean for the future of medicine
By the end, you’ll understand why viruses are not only something to fear, but something we may one day rely on to save lives.
Click the link in our bio to listen now, or search ‘ZOE Science & Nutrition’ wherever you listen to podcasts. 🎧
Did you hear about orforglipron, the new GLP-1 pill in the headlines this week?
A new randomised control trial, published in Nature Medicine (PMID: 42120723), explored the effects of this daily pill which activates the GLP-1 receptor.
My key takeaways:
👉🏼 People who take the pill can maintain their weight loss for up to a year after treatment with injectable GLP-1 medicines
👉🏼 The trial also found promise for people who had previously used GLP-1 injections and reached a weight-loss plateau, helping to prevent weight regain
👉🏼 A significantly reduced appetite, caused by this medication, increases the risk of malnutrition if nutrition isn’t carefully managed
👉🏼 Gastrointestinal side effects may be improved through dietary support, including fibre, hydration and regular meal timing
👉🏼 Less than 5% of people accessing these drugs are doing so through their doctor or the NHS, meaning the risks are higher, particularly if you don’t have weight to lose
👉🏼 Limitations: 1 year duration not ‘for life’ as some headlines suggest, no comparator arm using the injectables so not directly compared to continuing the existing drug and funded by Eli Lily who make the drug
This is an exciting advance in medical science but it requires careful consideration and nuance.I explore this topic in more detail in my new book, The Appetite Reset, out 25th June (link in bio 💚).
I wanted to share a personal story that sits at the heart of my upcoming cookbook, Good Mood Food.
My mother now has dementia and lives in a care home. She no longer recognises me. I know many of you will understand just how devastating a loved one living with dementia can be.
Witnessing her decline over the last decade has made me determined to better understand how everyday choices, including what we eat, might support brain health earlier in life.
We now know that the gut and brain are in constant conversation, and that what we eat can influence how we feel, as well as aspects of brain function over time.
At @zoe, one of the most consistent things we see in our research is that when people begin to eat a more varied, plant-rich diet, many report noticeable improvements in their mood and energy.
The idea for Good Mood Food grew from these insights.
Inside, you’ll find over 100 recipes designed to be both uplifting and nourishing; food that supports your gut, your brain, and how you feel day to day.
From some of my most comforting favourites to brighter, more vibrant dishes, these are recipes to cook, share, and come back. Delicious meals to boost your gut microbes, your tastebuds, and your mood.
I really hope you enjoy them.
1/3 of adults now have seasonal allergies like hayfever. Food allergies now affect 1 in 20 children, and can be life threatening.
Food intolerances and allergies were once vanishingly rare, but within a single generation, they have exploded. And 200 years ago, seasonal allergies were completely unknown.
So what’s changed, and why are they rising so rapidly?
@dradamfox is one of the world’s leading allergy experts and Professor at King’s College London. He received an OBE for his contribution to reshaping medical approaches to allergies.
In this week’s episode, we unravel:
• Why allergies have risen so dramatically
• The difference between allergies, intolerances, and sensitivities
• What’s happening inside your body during a reaction to pollen, peanuts or gluten
• How to reduce your symptoms
•And new approaches that can actually cure allergies
By the end of this episode, you’ll understand why allergies are increasing, what’s driving them, and how to reduce your symptoms.
Click the link in our bio to listen now or search ‘ZOE Science & Nutrition’ wherever you listen to podcasts.
Who says hummus has to be made with chickpeas? 🫘
This roasted carrot and kidney bean dip is creamy, colorful, and packed with plants to support your gut health.
Roasted carrots are full of natural sweetness along with prebiotic fibers and beta-carotene, which support gut and immune health. Kidney beans add fiber and resistant starch, key fuels for beneficial gut microbes that produce compounds linked to better metabolic health.
Garlic provides additional prebiotic compounds to help your gut microbes thrive, while tahini and extra virgin olive oil add healthy fats that support the absorption of fat-soluble nutrients.
And if you want to take your fibermaxxing to the next level, top it off with ZOE Daily30; our whole food gut health supplement designed by ZOE scientists with over 30 plants, now available in the UK, US, Germany and Ireland. 🇩🇪 🇮🇪 🇬🇧 🇺🇸 More countries coming soon!
Find the full recipe in our bio.
What’s your take, is it still hummus if there isn't a chickpea in sight?
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